新靶标与化学干预研究中心线上学术报告会

时间：2022年12月14日上午10:00-11:00

参会方式：Zoom，会议ID：840 7769 9163 会议密码：026754

线下参会地点：图书馆8楼809会议室

题目：Structure-Based Drug Discovery-A Case Study

报告人：Dr. Youla S. Tsantrizos is currently a Full Professor at the Department of Chemistry and an Associate Member of the Department of Biochemistry at McGill University. She obtained her Ph.D. in Organic Chemistry in 1990 from McGill University and then pursued Post-Doctoral studies at Brown University from 1990 to 1991. In 1997, she joined the Department of Chemistry as Senior Research Scientist at Boehringer Ingelheim (Canada) Ltd. During her 11 years career at Boehringer Ingelheim, she held a number of leadership roles in medicinal chemistry and participated in activities that moved a number of antiviral agents through the different stages of the drug discovery process, including lead optimization, pre-clinical and clinical development. Dr. Tsantrizos’ lab is currently investigating four biological targets: the human 1. farnesyl pyrophosphate synthase (hFPPS), 2. geranylgeranyl pyrophosphate synthase (hGGPPS), 3. metalloproteinase ZMPSTE24, and 4. the HIV-1 reverse transcriptase (RT). These studies are multidisciplinary, involving a seamless integration of synthetic organic chemistry, structural research, and biochemistry.

校科研处，生命科学研究院

2022年12月12日